All You Need to Know About Rejuran (AKA the PDRN / Salmon DNA Facial)

By the Beauty Ranch Medical Spa team, led by Nurse Jamie — Brentwood, Los Angeles

The short answer: Rejuran is Korea''s most famous skin treatment — polynucleotides (PDRN) derived from salmon DNA that repair and regenerate skin at the cellular level, improving texture, elasticity, fine lines and glow. At Beauty Ranch in Brentwood we deliver Rejuran with the Potenza microneedling infusion tip (no RF) so the PDRN reaches deeper than topical application. Rejuran Infusion Facial: $1,200 (currently special-priced from $1,800 — see specials), or add Rejuran PDRN to any microneedling treatment for $600.

What Is Rejuran?

Rejuran (Rejuran Healer) is the K-beauty phenomenon that put "skin quality" treatments on the map. Its active ingredient is PDRN — polydeoxyribonucleotides — DNA fragments derived from salmon, which are remarkably biocompatible with human skin. PDRN signals skin cells to repair: stimulating collagen, improving elasticity, calming inflammation and strengthening the skin barrier. Loved in Seoul for years, it went viral worldwide as the "salmon sperm facial" — and yes, that''s the same treatment.

Why It''s Called the Salmon Sperm (or Salmon DNA) Facial

The PDRN in Rejuran is extracted and purified from salmon DNA. The nickname stuck because it''s unforgettable — but what matters is the science: salmon polynucleotides are structurally close enough to human DNA to trigger regeneration without reaction, which is why dermatologists in Korea have used PDRN for skin repair for over a decade. Celebrities from Jennifer Aniston to Kim Kardashian have made "salmon sperm facials" famous in the US — Beauty Ranch is one of the few Los Angeles med spas actually offering the real thing.

Why We Deliver Rejuran With the Potenza Infusion Tip

Most places apply PDRN topically after microneedling and hope it soaks in. At Beauty Ranch, we use the Potenza system''s dedicated infusion tip (no RF) — which creates precise micro-channels and drives the Rejuran into the skin as the channels open, before they begin closing. Deeper, more uniform delivery; more of the product where it works.

What Does Rejuran Improve?

Overall skin quality and "glass skin" glow, fine lines and early wrinkles, texture and enlarged pores, post-acne marks and weakened skin barrier, elasticity and crepiness. It''s a regenerator, not a filler — skin looks like itself, healthier.

Can Rejuran Be Used Under the Eyes?

Yes — the delicate eye area is one of the most popular zones for PDRN treatment in Korea, where it''s used for crepiness, dark circles and fine lines. Ask at your consultation and we''ll map the right approach for your eye area.

What Is a Rejuran Session Like?

Numbing cream for 30 minutes, then the infusion treatment — about 30 minutes of light microneedling sensation. Expect pinkness for 24–48 hours and tiny papules at first that settle as the PDRN absorbs. Glow appears within days; the regenerative results build over weeks. Most clients do a series of 3–4 sessions spaced 2–4 weeks apart, then maintain quarterly.

Rejuran Pricing at Beauty Ranch (Brentwood, Los Angeles)

• Rejuran Infusion Facial (Potenza infusion tip) — $1,200 (reg. $1,800, current special)
• Rejuran PDRN add-on to any microneedling treatment — $600

Special pricing rotates monthly — check our monthly specials.

Rejuran vs. Other Skin Boosters

Rejuran is a regenerator, not a filler or a hydrator. Unlike hyaluronic-acid skin boosters (which plump and hydrate), PDRN works at the cellular level — telling the skin to rebuild itself. Many clients combine the two for the full "K-beauty glass skin" effect.

Why Beauty Ranch

Located in Brentwood at 140 S Barrington Place, Los Angeles 90049 — minutes from Santa Monica, Westwood, Pacific Palisades and Bel Air. Founded by celebrity skincare expert Nurse Jamie — an early adopter of K-beauty treatments in Los Angeles — with the Potenza infusion technology most med spas don''t have.

Ready to try Rejuran? Book a consultation or call (310) 587-3502.

Frequently Asked Questions

What is Rejuran?

Rejuran is a Korean skin-regeneration treatment whose active ingredient, PDRN (polynucleotides derived from salmon DNA), signals your skin to repair itself — improving texture, elasticity, fine lines and glow.

Is Rejuran the same as the salmon sperm facial?

Yes. "Salmon sperm facial" and "salmon DNA facial" are nicknames for PDRN treatments like Rejuran — same science, viral name.

What is PDRN?

Polydeoxyribonucleotide: purified DNA fragments from salmon that are highly compatible with human skin and trigger cellular repair, collagen production and barrier strengthening. It''s been used in Korean dermatology for over a decade.

How much does Rejuran cost in Los Angeles?

At Beauty Ranch in Brentwood: the Rejuran Infusion Facial with the Potenza infusion tip is $1,200 (currently special-priced from $1,800), or add Rejuran PDRN to any microneedling treatment for $600.

How many Rejuran sessions do I need?

A series of 3–4 sessions, 2–4 weeks apart, delivers the signature result, with quarterly maintenance after.

Is there downtime after Rejuran?

Pinkness for 24–48 hours and tiny bumps at first that settle as the product absorbs. Most clients are back to normal (with glow) within two days.